Bupivacaine hydrochloride
CAS: 14252-80-3
Zuiverheid: 99%
MW: 324.89
MF: C18H28N2O. ClH
Uiterlijk: White powder
Bupivacaine Hydrochloride Description:
Bupivacaine Hydrochloride is 2-Piperidinecarboxamide , 1-butyl-N(2,6dimethylphenyl)-,monohydrochloride , monohydrate , a white crystalline powder that is freely soluble in 95 percent ethanol , soluble in water , and slightly soluble in chloroform or acetone.Bupivacaine Hydrochloride is available in sterile isotonic solutions with and without epinephrine(as bitartrate) 1 : 200 ,000 for injection via local infiltration,peripheral nerve block , and caudal and lumbar epidural blocks . Solutions of Bupivacaine Hydrochloride may be autoclaved if they do not contain epinephrine . Solutions are clear and colorless. Bupivacaine is related chemically and pharmacologically to the aminoacyl local anesthetics .They differ in this respect from the procaine-type local anesthetics , which have an ester linkage.
Bupivacaine 0.25% en 0.5% options are utilised for the production of local anaesthesia by percutaneous infiltration, peripheral nerve block(s) and central neural block (caudal or epidural), that may be, for specialist use in locations where prolonged anaesthesia is indicated. Bupivacaine without adrenaline may possibly also be made use of for intradural spinal anaesthesia. Bupivacaine is particularly beneficial for discomfort relief e.g. for the duration of labour, as its sensory nerve block is more marked than its motor block. A list of indications and recommended dose and strength of solution proper for each are shown in the table under ‘Posology and system of administration’.
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